First Author:   Kazumitsu Nawata University of Tokyo nawata@tmi.t.u-tokyo.ac.jp   7-3-1 Hongo, Bunkyo-ku Tokyo, 113-8656, Japan   81-3-5841-8756(Phone) 81-3-5841-8756(Fax) Second Author: Koichi Kawabuchi Tokyo Medical and Dental University kawabuchi.hcer@tmd.ac.jp   Tokyo, 113-8549, Japan